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Translational Science

Discovery & Development Drug Discovery

The Bumpy Road to a Cytomegalovirus Vaccine

| Andy Lane

The development of a CMV vaccine has been 50 years in the making.

Discovery & Development Clinical Trials

Failing Safely: Why Ending Some Programmes Early May Be a Recipe for Successes Later

| Adrian Wildfire

Why are compounds still failing at the final hurdle?

Manufacture Advanced Medicine

Driving CAR T Cell Therapy

| James Strachan

John Rossi, Director of Translational Sciences at Kite Pharma, talks about bright future of CAR T cell therapy.

Discovery & Development Clinical Trials

Getting on Target for Alzheimer’s

| Neil Cashman, James Kupiec

"Biogen revitalizes hope for Alzheimer’s therapy, but their work highlights why we still need greater selectivity."

Discovery & Development Drug Delivery

Beyond the Barrier

| Maryam Mahdi

Can bacterial viruses improve drug delivery to the brain?

Discovery & Development Drug Discovery

From Cynicism to Success

| With Colleen Cutcliffe

Some have dismissed excitement about the microbiome as “hype,” but real results are beginning to be seen.

Discovery & Development Drug Discovery

Putting Patients First

| Carlo Toniatti

Oncology research has come a long way over the past 30 years, but we must transform outdated practices to further improve drug discovery innovation.

Discovery & Development Clinical Trials

Of Men and Mice

| James Strachan

Male animal bias in preclinical research isn’t scientifically justified and may be skewing our understanding of the brain.

Discovery & Development Clinical Trials

Choice Matters

| Maryam Mahdi

A new vaccine could help give people at risk of HIV more options.

Discovery & Development Drug Discovery

Putting the Brakes on Aging

| Maryam Mahdi

Sitting Down With… Joan Mannick, Co-Founder and Chief Medical Officer at resTORbio, Massachusetts, USA.

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