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Manufacture Advanced Medicine

Regulate with the Times

| Claudia Zylberberg

Claudia Zylberberg explains the importance of ancillary material quality for advancing cell and gene therapies.


Manufacture Advanced Medicine

Manufacturing by Design

| Frederic Revah

Let’s reduce gene therapy manufacturing costs by optimizing cell lines, improving transfectants, and optimizing downstream purification.

Discovery & Development Clinical Trials

Failing Safely: Why Ending Some Programmes Early May Be a Recipe for Successes Later

| Adrian Wildfire

Why are compounds still failing at the final hurdle?

Business & Regulation Business Practice

Greater Transparency; Fewer Shortages

| Dawn MacNeill

Only when greater transparency is established in supply chains can the industry begin to iron out problems with drug shortages.

Manufacture Ingredients

Food for Thought

| Araksya Topchyan

If we learn more about drug–nutrient interactions, we may be on the path towards better medicines.

Business & Regulation Business Practice

For the Many

| Charles Gore

The pharmaceutical industry must be encouraged to look beyond patients in advanced economies.

Manufacture Small Molecules

The Excipient of the Future

| Dieter Lubda

How will the adoption of novel approaches to the development of excipients help overcome the challenges of poorly soluble APIs?

Manufacture Advanced Medicine

The CRISPR Toolbox

| Garrett Rettig

"Moving beyond Cas9 may be the secret to reducing CRISPR’s off-target effects," says Garrett Rettig.

Manufacture Advanced Medicine

Unprecedented Growth – and Challenges

| Philip W. Wills

Now that Gene therapy's promise has been shown, the industry must focus on improving the manufacturing process and bring down costs.

Manufacture Advanced Medicine

The TCRs Are Coming

| Miguel Forte

Miguel Forte argues it’s time to fine tune the way we target solid tumors...

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