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Manufacture Drug Delivery

Drugs in Disguise

How to dress drugs to help them survive in the bloodstream.

Manufacture Drug Delivery

Plant Protein Potential

| Stephanie Vine

Can lettuce really help biopharmaceuticals turn over a new leaf? Researchers certainly think so.

Business & Regulation Business Practice

M&A Merry-Go-Round

| Charlotte Barker

Round and round she goes, where she stops nobody knows. How will the current merger and acquisition fever affect the industry?

Discovery & Development Business Practice

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies

The rapid growth of the therapeutic antibody market has increased the interest in modeling of the antibody structure...

Discovery & Development Business Practice

Application of microcalorimetry in drug discovery at Exelixis

In this report, we illustrate the utility of calorimetry in making better laboratory decisions.

Discovery & Development Business Practice

Evaluating the rheological properties of hyaluronic acid hydrogels for dermal filler applications

This study shows how rheology and particle size measurements can be used to characterize the physical properties of HA dermal fillers.

Discovery & Development Business Practice

The application of MicroCal VP Capillary DSC at a contract development organization

A case study involving the formulation development of a monoclonal antibody is presented to detail the utility and potential limitations of DSC in support of preformulation for a variety of protein products.

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 4

| Sponsored by Malvern Panalytical

In Part Four, we address frequently asked questions related to the application of DLS to the characterization of protein therapeutic formulations.

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 3

| Sponsored by Malvern Panalytical

In Part Three, we cover the basic types of DLS deconvolution algorithms used to extract the intensity weighted particle size distribution from the measured correlogram.

Discovery & Development Drug Delivery

Overview of Key Principles of Dynamic Light Scattering to protein therapeutic formulations – Part 2

| Sponsored by Malvern Panalytical

In Part Two, we cover the influence of concentration effects and particle interactions on DLS results and provide a roadmap for identifying and distinguishing each type of concentration effect.

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