Scaling CRISPR Gene Correction for Sickle Cell Disease
November 9, 2026
Researchers establish a clinical-scale, nonviral manufacturing process that directly repairs the disease-causing HBB mutation in autologous stem cells
2 min read
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Research News
Naive-Like T Cells Linked to CAR T Durability
November 4, 2026
Higher proportions of less-differentiated T cells were associated with longer progression-free survival in a 783-patient lymphoma analysis
1 min read
BMS Details Patient Death in Zola-Cel Multiple Sclerosis Trial
November 3, 2026
The company also reported early efficacy and safety data from the Phase I Breakfree-2 study
2 min read
What Will It Take to Control Continuous Biomanufacturing?
November 2, 2026
Review examines how PAT, model-based control, reinforcement learning, and digital twins could maintain product quality from perfusion culture through downstream purification
2 min read
Off-the-Shelf CAR T Shows Early Signal in Progressive Multiple Sclerosis
November 2, 2026
Phase I data show B-cell depletion and mostly stable or improved disability scores, but the uncontrolled study remains small and follow-up is limited
2 min read
Prime Editing Creates Drug-Controllable T Cell Therapies
October 28, 2026
Engineered T cells resisted tacrolimus but remained sensitive to cyclosporin, providing a potential way to select or suppress them after administration
2 min read
Engineering a New Generation of Cancer-Fighting Cells
October 28, 2026
USC researchers develop a scalable cell engineering platform that could overcome key manufacturing and therapeutic limitations of CAR-based immunotherapies
2 min read
Is Stem Cell Therapy Quality Control Missing Proteotoxic Cargo?
October 26, 2026
Review calls for senescence screening and EV proteomic profiling to assess whether cell therapy products can maintain protein homeostasis after transplantation
2 min read
Engineering CAR T Cells Inside Solid Tumors
October 26, 2026
Researchers develop targeted lipoplex platform that generates CAR T and NK cells directly within tumors, improving survival in preclinical breast cancer models
2 min read
CAR NK Cells Target Cancer and Autoimmunity
October 21, 2026
mRNA nanoparticles reprogram NK cells in vivo, inducing tumor remissions and reducing autoimmune liver damage in mice.
2 min read
