Gene Therapy Approach Shows Promise for Hydrocephalus
October 20, 2026
Researchers develop AAV-based method to target cerebrospinal fluid production, revealing new insights into postnatal neurogenesis
2 min read
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Research News
SRSF1 Gene Delivery Extends Lifespan in Aged Mice
October 19, 2026
An RNA sequencing and machine learning screening platform identified an RNA-processing factor that reduced markers of cellular aging without erasing cell identity
2 min read
Three Targets, One CAR T Therapy
October 19, 2026
First-in-human study demonstrates the potential of rapidly manufactured trispecific CAR T cells to deliver durable remissions in B-cell lymphoma
3 min read
CRISPR Cuts Cholesterol for a Year
October 14, 2026
A single CRISPR infusion sustained reductions in LDL cholesterol and triglycerides for 12 months.
2 min read
Pregnancy After CAR T Shows Early Promise
By Mouj Hijazi
October 7, 2026
No autoimmune disease flares occurred across 14 pregnancies after CAR T-cell therapy, with 8 healthy babies born and 5 pregnancies ongoing.
3 min read
When CAR T Cells Linger in the Gut
By Mouj Hijazi
October 7, 2026
Persistent CAR T cells and widespread immune disruption may help explain a rare form of severe intestinal inflammation after BCMA-directed therapy
3 min read
Building a Pre-Disease Data Map
October 7, 2026
Mayo Clinic and Thermo Fisher launch a large-scale multi-omics resource designed to reveal disease before symptoms appear
2 min read
Vyriad Begins First-in-Human Trial of In Vivo CAR T Therapy VV169
September 28, 2026
Phase I study will test whether a targeted lentiviral vector can generate BCMA-directed CAR T cells inside patients with multiple myeloma
3 min read
MAPK Inhibitors Restore CAR T-Cell Target in Thyroid Cancer Models
September 24, 2026
Trametinib and dabrafenib increased TSHR expression and improved the activity of CAR T cells in a patient-derived model of anaplastic thyroid cancer
2 min read
“Plug-and-Play” CAR T Platform Enables Post-Infusion Retargeting
September 23, 2026
Meditope-enabled CAR T cells can be tracked, selectively expanded, and directed toward additional tumor antigens using externally administered protein adaptors
2 min read
