Evolve your Upstream Process with Innovative Cell Culture Solutions

Empowering scientists with cutting-edge solutions for enhanced productivity and product quality in cell culture

In today’s competitive biopharmaceutical landscape, scientists face challenges like speed to market, process economics, and quality assurance. At Merck, we provide effective solutions rooted in our deep chemical and cell culture expertise, continually pushing the boundaries of innovation. Novel approaches such as cell culture media fingerprinting, along with high-performing cell lines and media, empower you to meet production goals. With rigorous raw material characterization, robust quality management systems, and all our sites certified under the EXCiPACT GMP standard for cell culture media, we prioritize quality and reliability.

Explore the resources below to transform your upstream processes into success!

New CHOZN® Elite Cell Line: Boost Your Yield and Achieve High Titers

Discover the CHOZN® Elite cell line – a next generation CHO host for both fed-batch and perfusion processes. The cell line is plug-and-play with your established cell line development process and enables high producing clones, achieving a titer of 7-13 g/L. Find more details in our data sheet!

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Cell Culture Media Fingerprinting Service: Innovation at Your Fingertips

Explore Cell Culture Media Fingerprinting, an innovative analytical method that empowers rapid and reliable quantification of 100+ media components – simultaneously! Achieve unparalleled accuracy in media identification with just one assay, minimizing risks from limited media understanding and batch-to-batch variability.

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Mastering Glycosylation for Improved Biopharma Production Outcomes

Unlock the power of glycosylation in monoclonal antibodies (mAbs) and other recombinant proteins, optimizing their efficacy, stability, and immunogenicity. Join our webinar to learn from industry experts how the Cellvento® ModiFeed Platform enables precise modulation of glycosylation profiles, enhancing product quality and consistency without compromising performance.

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Select the Right CHO Cell Culture Media and Feeds to Enable Your Next Breakthrough

Access our Media Selection Guide for an overview of CHO media and feeds designed for high-performance monoclonal antibody and recombinant protein production. Receive expert guidance on selecting the optimal medium for your process!

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Advancing Upstream Processes with Custom Cell Culture Media Development

Want to accelerate your development timeline with customized platform media or enhance critical quality attributes with precise feeds for your next blockbuster molecule? Explore our custom cell culture media development workflow, featuring flexible project designs. We utilize high-throughput screening of diverse media libraries and apply advanced statistical tools like MVDA to maximize performance.

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Optimizing Biopharmaceutical Production with Intensified Fed-Batch Strategies

Learn about the impact of feeding schedules and nutrient management to streamline your development process. Discover how optimized feeding strategies using Cellvento® ModiFeed Prime feed in intensified fed-batch processes can enhance productivity and efficiency, achieving equivalent results in shorter timelines.

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Streamline Your Custom Media and Chemicals Requests with mConfig™ Configurator

Discover how the mConfig™ Cell Culture Media and Chemicals Configurator simplifies requesting custom products. With real-time recommendations backed by extensive R&D expertise, mConfig™ Configurator empowers you to optimize formulations and supports informed decision-making. Access the datasheet for detailed insights!

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