Navigating the Complexities of Small Molecule Production

Rely on a committed CDMO with proven expertise for the success of your small molecule program.

Selecting a Contract Development and Manufacturing Organization (CDMO) is a challenging task in a crowded market and competitive landscape. By prioritizing Safety and Sustainability, Quality, and Delivery in your CDMO selection process, you can enhance your outsourcing strategy and ensure alignment with your goals. 

With 35+ years of proven chemical synthesis production, Merck offers Small Molecule CDMO services and reliable drug substance supply for: 

  • Small Molecule APIs 

  • High potency APIs (HPAPI) 

  • Linker/Payload 

  • Custom PEGs 

Handling Protocols: Key Considerations in the Highly Potent API Market Whitepaper

Highlighting the importance of specialized facility design, robust handling programs, and protective measures for personnel, this whitepaper discusses the complexities and safety protocols involved in the manufacturing of highly potent active pharmaceutical ingredients (HPAPIs). It emphasizes the need for stringent containment strategies and continuous improvement to ensure safety and compliance.

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Sustainability by Design in API Manufacturing Webinar

This webinar highlights the need for sustainability in small molecule API production, which significantly contributes to global emissions. It addresses sustainability challenges and regulatory pressures in API manufacturing, offering strategies for improving chemical process design. Experts share case studies on selecting a CDMO that prioritize sustainability while ensuring efficiency and safety.

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Integrating Phase-Appropriate Quality Standards tech note

A phase-appropriate quality approach provides agility and cost savings by focusing on requirements for early-phase programs while keeping long-term goals in view. Collaborating with an experienced CDMO with a proven track record in implementing this strategy helps set clear expectations and requirements, balancing the need for accelerated timelines during product development.

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Patients Can’t Wait: A Case Study for Overcoming Obstacles on the Journey to Commercialization Webinar

The webinar emphasizes the importance of a client-focused approach in the journey to commercialization. It presents case studies showcasing the value of partnering with a CDMO for API and HPAPI development, highlighting custom solutions and flawless project management to overcome challenges in delivering new medicines to patients efficiently.

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Capacity Update: Small Molecule Drug Substance/API Webinar

To ensure the success of your program, you need a reliable and committed CDMO to meet your needs and navigate complexity with you. With 35+ years of experience, expert capabilities and capacity, Merck is the partner to support you every step of the way.

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Infographic Tackling The Toughest Small Molecule Challenges

Accelerating drug development is of utmost importance for bringing new drugs to patients faster, but the increased complexity in API production poses many challenges. Discover how to accelerate your program with a strategic CDMO partner with the experience, expertise, and flexibility required to solve the toughest small molecule challenges.

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