Process: Intensified. Drug Manufacturing: Accelerated
Secure Your Competitive Edge With Process Intensification
In today’s rapidly changing industry, manufacturers need to reduce drug costs and increase productivity to stay competitive. It’s never been more important to intensify — and with expert insight, cutting-edge solutions, and maximized value, it’s never been easier.
Time to Intensify: Taking mAb Manufacturing to the Next Level
Explore how end-to-end process intensification (PI) can transform your mAb manufacturing strategy. This white paper outlines practical, scalable approaches to upstream and downstream intensification—including analytical strategies—supported by real-world results, technology guidance, and expert insights.
On-Demand Webinar | It's Never Too Early to Intensify: Upstream Process Intensification
With complexity increasing and nearly 50% of protein therapies being produced at low volumes, multi-product facilities are becoming essential — and process intensification is a key strategy to improve cost-efficiency and access to medications. Explore approaches to expedite your development, from digital solutions to automation.
Process Intensification: Challenges, Trends, and Industry Takeaways
"It's no longer a case of 'if' and 'when,' the fact is it's happening now." Experts unpack the realities of process intensification. Watch the video below
Success Story: Increased Productivity With Concentrated Fed-Batch
A large biopharma company wanted to establish a single-use multi-product facility by choosing appropriate upstream processes that can deliver more than 500 kg/year throughput. Consequently, a concentrated fed-batch process was established, enabling higher productivity and increasing the throughput (up to 4× higher titer than standard fed-batch), providing more flexibility for production runs.
DownloadSuccess Story: Resolute® BioSMB for Increased Productivity at the mAb Capture Step
Our experts recommended that a CDMO upgrade from traditional batch chromatography to the BioSMB multi-column chromatography platform to achieve higher productivity at the mAb capture step. Read how the CDMO saw dramatic improvements in both resin utilization and measured productivity.
DownloadIntegrated | Connected Downstream Processing of mAbs With Resolute® BioSC for Improved Productivity, Cost, Footprint, and Facility Utilization
In this application note, we build on previous work by implementing a new intensified process platform in connected mode with the Resolute® BioSC. Get guidance on implementing a step-wise intensification approach for mAb production, learn how the Resolute® BioSC enables efficient process integration, and discover the productivity gains offered by connected processing at lab and pilot scales.
DownloadIntensifying Upstream Processing and the Implications for Media Management
This whitepaper provides the tools and information needed to consider process intensification (PI) options while evaluating the implications of media management. This comprehensive overview of the media journey and how increased volumes associated with PI can be effectively managed is followed by an exploration of the feasibility of different PI scenarios in both new and existing facilities.
DownloadOn-Demand Webinar: Overcoming Facility Constraints Posed By Process Intensification
Biopharma manufacturers know the potential of process intensification, but many do not see how their current facility layout and process flow can get in the way of achieving that full potential.
Join Sartorius experts as they look at current facility designs around USP and DSP through the lens of Process Intensification to see how changes in layout and process flow can overcome perceived constraints such as media and buffer consumption.
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