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There’s plenty to consider when scaling your upstream process, such as cell line characteristics, shear sensitivities and hydrodynamics – Yasser Kehail explains, step-by-step, what’s involved.
Over the course of six episodes, we'll be discussing everything from digitalization to continuous manufacturing to protein A capture to get you off to a flying start on your own bioprocess intensification journey
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September 16, 2020
What is bioprocess intensification? Why is it important? Bill Whitford introduces the series and shares his thoughts on digitalization and process automation.
September 30, 2020
Is continuous the way to go? Avril Vermunt discusses the benefits over batch, the first things to consider, and common pitfalls when connecting your process.
October 14, 2020
Andreas Castan discusses the opportunities for efficiency gains in upstream manufacturing, including: the seed train, production bioreactor and perfusion.
Discussing the use of different expression formats, from transient through to stable clones, when using Chinese Hamster Ovary cells for biotherapeutic protein production, experts from Lonza and Denmark Technical University share the key considerations of selecting an expression format during biotherapeutic development, and how Lonza’s GS Discovery® solution addresses these.
mRNA therapeutics manufacturing has been a major industrial talking point since its development during the COVID-19 pandemic. Now that CDMOs are developing the technologies and the capacities to scale it up, we find out just how much potential there is in this sector.
Conversations about drug formulation with experts from Merck, hosted by The Medicine Maker.
The Medicine Maker presents a 6 episode series on the inspiring efforts of the Drugs for Neglected Diseases initiative. Tune in and learn just what it takes to develop medicines for some of the world’s most neglected patient populations.
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