The Power List 2021 – Biopharmaceuticals
Chief Scientist and Head of External R&D at GlaxoSmithKline
Considered one of the world’s leading vaccine experts, Rappuoli was involved in the development of CRM197 used in H. influenzae, N. meningitidis, and pneumococcus vaccines, and has introduced several novel scientific concepts. He is also actively involved in research and development. Rappuoli and a team of Italian scientists at the Monoclonal Antibody Discovery Lab have been conducting extensive work on SARS-CoV-2 and recently demonstrated three mutations that allow the virus to evade the polyclonal antibody response of highly neutralizing convalescent plasma.