This webinar delves into the cutting-edge intersection of chemistry and biology, showcasing how targeted molecular innovation is driving the next generation of life science and diagnostics products. It will explore two distinct, yet interconnected, areas of advanced innovation:
Precision Glycosylation Modulation: The presentation will examine how the deliberate modulation of glycosylation pathways, a critical quality attribute in biopharmaceutical development, can significantly enhance the consistency and efficacy of therapeutic proteins. A particular focus will be placed on the innovative use of fluorinated monosaccharides as metabolic modulators to precisely influence these crucial glycosylation patterns.
Advanced Biocatalysis for Sustainable API Synthesis: The webinar will highlight the expanding and pivotal role of biocatalysis in the synthesis of Active Pharmaceutical Ingredients (APIs). Beyond its efficiency, the discussion will emphasize biocatalysis's contribution to green chemistry and sustainable manufacturing. Attendees will see examples of blockbuster drugs produced using well-known enzyme families (e.g., lipases, ketoreductases, transaminases), as well as the emerging application of more exotic, nature-derived biocatalysts. Specific examples will demonstrate enzymes utilizing, adding, or modifying carbohydrates for API synthesis, small molecules, and biologics.