5 Key Takeaways

• 1

  Raman spectroscopy offers rapid, label-free insights into viruses and host responses, enhancing pandemic preparedness.

• 2

  Enhanced Raman techniques like SERS, TERS, and CARS improve sensitivity and resolution for detecting viral particles.

• 3

  Raman-based methods have shown rapid detection capabilities for influenza and high accuracy for SARS-CoV-2 in saliva.

• 4

  Research focus is skewed towards accessible viruses, leaving high-risk pathogens like Lassa and Marburg underexplored.

• 5

  Technical barriers such as weak signal intensity and fluorescence interference hinder the clinical translation of Raman methods.