Discovery & Development Dosage Forms, Drug Delivery, Formulation, Small Molecules

Co-Crystals Shine in Innovation Awards

Celebrating the winner of our annual Innovation Awards: a service for co-crystal prediction

03/14/2025 | 1 min read | News

The mPredict Co-Crystal Prediction Service from Merck KGaA, Darmstadt, Germany, is the winner of The Medicine Maker 2024 Innovation Awards! The service uses an AI-based tool to predict optimal co-formers for an API that will result in co-crystals with improved solubility and stability. According to Merck, the process is 96 percent faster than traditional experimental screening – and also uses fewer resources. Around 70 percent of drugs in development pipelines are thought to have solubility and/or bioavailability issues.

The Innovation Awards are our annual tradition to celebrate new drug development and manufacturing technology launches. For 2024, we received a record number of nominations. The grand winner was decided via a reader vote. You can look forward to reading the story behind the mPredict Co-Crystal Prediction Service in a future article.

Tied for the position of runner up are two technologies developed through collaboration:

FDmiX, developed by Lonza, FDX Fluid Dynamix, and Fraunhofer IPK. This mixer specially designed for mRNA encapsulation.
Constellation with cryoFIL, developed by Cellular Origins and 3P innovation, to automate and streamline filling processes in cell and gene therapy workflows.

Nominations for the 2025 Innovation Awards will open soon. Sign up for our newsletter to be the first to find out when the nomination form is live.

In 2023, our grand winner was Lonza’s Enprotect Capsule. You can read an interview with the winner here.

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