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Small Molecules

Discovery & Development Clinical Trials

Inhibitors Versus Diabetes … And Dementia!

| Rob Coker

Research suggests diabetes patients using SGLT-2 and DPP-4 inhibitors have a decreased risk of developing dementia.

Manufacture Quality & Compliance

Facing Up to the New Nemesis of Pharma: Nitrosamines

| 8 min read

What’s going on with nitrosamines? Naiffer Romero from the USP walks us through frequently asked questions.

Manufacture Technology and Equipment

The Nonprofit Model for Manufacturing

| Stephanie Vine | 13 min read

Civica Rx is approaching generic drug manufacturing using a nonprofit model – and it’s working. We get the story behind their facility in Petersburg.

Business & Regulation Supply Chain

Where Have All the Drugs Gone?

| 6 min read

Drug shortages are everywhere. We speak with Vimala Raghavendran at the US Pharmacopeia to get the full picture.

Business & Regulation Profession

The Power List 2025: Nominations Are Open

Who deserves a place on our annual list of inspirational and influential industry professionals?

Manufacture Small Molecules

How to Optimize Your API

| Richard Castledine | 4 min read

Tips to identify a safe, cost-efficient, and sustainable route to scalable API synthesis

Discovery & Development Drug Discovery

Predictive AI in Drug Discovery: Five Steps to Success

| Mirit Eldor | 5 min read

The use of AI in small molecules drug discovery is driving the sector in big ways – but there are big challenges too. Here are five steps to success

Manufacture Small Molecules

Another Chance for Arsenic

| Carole Nicco | 4 min read

The repurposing of legacy small molecules drugs could be more advantageous than previously known. Case in point: Arsenic

Manufacture Small Molecules

Moving with the Times

| Julian Northen | 6 min read

Patient needs are changing, but small molecule drugs remain as important as ever. Here are some tips for development success.

Discovery & Development Drug Discovery

Combination Revelation

| Rob Coker | 2 min read

Could J&J’s combination treatment for PAH bridge the gaps between guidelines and practice, while easing the burden on patients?


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