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Discovery & Development Business Practice, Clinical Trials, Ingredients, Formulation, Technology and Equipment, Small Molecules, Bioprocessing - Single Use Systems, Dosage Forms, Analytical Science, Trends & Forecasts

Detecting agglomerates within pharmaceutical formulations

This article provides practical guidance on using automated particle image analysis to detect agglomerates in pharmaceutical formulations. Particle agglomeration has the potential to compromise clinical efficacy and must therefore be closely monitored and controlled during manufacture. Experimental data illustrate different strategies for the detection of agglomerates on the basis of size, shape and, where necessary, chemical identification.

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