Fast Track Your End-to-End Solution for Antibody-Drug Conjugates
The PROVEO Alliance combines three leading services to streamline antibody-drug conjugate development.
sponsored by Proveo
Looking for an experienced partner to simplify the development and manufacture of a new antibody-drug conjugate (ADC)? The PROVEO Alliance (PROVEO) combines the expertise of three established industry leaders – leading CDMO AGC Biologics, high-potency API (HPAPI) and bioconjugation specialist Cerbios, and fill and finish expert Oncotec – to deliver a start-to-finish solution for ADC development needs at all stages of the production process:
- Development of a microbial or mammalian cell line plus a production and purification process to deliver the purified binding protein part of the ADC (AGC Biologics)
- Design of an appropriate manufacturing process for payload, linker and bioconjugation with cGMP production of the ADC Drug Substance (Cerbios)
- Sterile filling and labeling of the drug product (Oncotec)
Together, the three companies bring over 75 years of know-how to the table. Plus, with sites in locations including Copenhagen, Seattle, Lugana, Dessau and Heidelberg, PROVEO is able to provide this integrated service on a global scale.
Streamlining services across quality assurance, process development, analytics and project management conveys clear advantages compared with using separate providers. One of the biggest benefits? Rapid development is the key offering – PROVEO is able to compress the usual timeline from DNA to fill-finish in as little as 20 months, compared with 30 months using separate providers. Guaranteed quality testing of the highest standard, with standardized quality targets and regular audits are further huge advantages.
The alliance allows seamless project management, with a single point of contact throughout the supply chain. So, whether you have questions about how AGC Biologics will fast-track manufacture and scale-up of your product, the latest purification strategies employed by Cerbios, or the robotic systems behind the 5,000 vials/hour fill speed of Oncotec, your contact will have the answer.
By offering the services of specialists across multiple teams within a single, global service backed by years of experience, PROVEO helps companies save time, cost and resources across all aspects of the ADC production cycle. The ultimate goal: getting potentially life-saving drugs to patients who need them faster.
