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Discovery & Development Drug Discovery

Fungal (Library) Growth

Thousands of biologically active secondary metabolites derived from different types of fungi have been analyzed and assigned to a library in a joint effort between the Hubrecht Institute, the Westerdijk Fungal Biodiversity Institute and Utrecht University in the Netherlands.

“An aging global population and the growing issue of drug resistance means that we need better and newer drugs, but the number of chemically distinct compounds that are being used in prescription drugs is limited. In addition, the active compounds in these drugs are often chemically related, relying on similar mechanisms to function,” explains research leader, Jeroen den Hertog from the Hubrecht Institute. “Fungi are known to produce pharmaceutically relevant compounds. And despite there being an estimated two million species of fungi, only a small fraction has been analyzed for their expression of biologically active compounds to date.”

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About the Author

Maryam Mahdi

Assistant Editor

After finishing my degree, I envisioned a career in science communications. However, life took an unexpected turn and I ended up teaching abroad. Though the experience was amazing and I learned a great deal from it, I jumped at the opportunity to work for Texere. I'm excited to see where this new journey takes me!

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