Lead by the Nose
The nose is not just an anatomical region for locally-acting drugs – it is an open door offering rapid access to different organs
Alain Regard and Pascale Farjas |
When considering drug delivery, the oral and injectable routes are perhaps the most well used and well discussed, but many interesting advances are being seen in the nasal drug delivery field that should not be overlooked. The main advantages associated with the nasal route are ease of use, direct access into the bloodstream, rapid onset of action, and avoidance of hepatic first-pass metabolism, to name just a few. The nasal mucosa’s proximity to the brain has also fuelled much interest in potentially using the nasal route to deliver drugs to the brain, although in practice this has proved challenging.
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