NanoSight Nanoparticle Tracking Analysis Concentration Measurement
The ability to compare concentration data across users, instruments and sites is a key requirement for many applications. Concentration repeatability and reproducibility are greatly improved with the application of the NTA concentration measurement upgrade, which has also been shown to reduce the influence of user selected capture and analysis settings on measurements. This application note describes the improvement in accuracy and precision of concentration measurements over a wide range of sample sizes, concentrations and materials.
Introduction
Nanoparticle tracking analysis (NTA) provides single particle size and concentration measurements. The growing popularity of the technique has driven the requirement to reduce user input, reduce variability and provide interlaboratory consistency in size and concentration measurements. The NTA concentration measurement has been modified to provide improved accuracy, precision and reproducibility of concentration measurements on a range of nanoparticle types, covering a broad size and concentration range. Concentration measurement repeatability and reproducibility have been greatly increased whilst removing measurement sensitivity to user settings over the recommended concentration range for NTA analysis.
