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Discovery & Development Drug Discovery, Digital Technologies

RePURPOSED

In sunny San Diego lies a library of drugs, which researchers are encouraging companies to exploit to repurpose old drugs for new needs. The open access drug catalog, ReFRAME, consists almost entirely of small molecules – all of which have reached the clinical development stage or undergone thorough preclinical filing – and is already showing results. Two compounds from the library have been identified as suitable treatments for tuberculosis and Cryptosporidium spp (1).

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  1. J Janes et al., “The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis,” PNAS 115, 10750-10755 (2018).

About the Author

Maryam Mahdi

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After finishing my degree, I envisioned a career in science communications. However, life took an unexpected turn and I ended up teaching abroad. Though the experience was amazing and I learned a great deal from it, I jumped at the opportunity to work for Texere. I'm excited to see where this new journey takes me!

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