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April 2024 Issue of The Medicine Maker

This is an issue of celebration! We celebrate inspiring and influential individuals in the pharma industry with our annual Power List, and then put the spotlight on the collective efforts of manufacturers and suppliers with our Company of the Year Awards, featuring categories such as Best Big Pharma, Best CDMO, and more. Also in this issue, experts discuss the ethical issues of advanced medicine, how AI can tackle drug shortages, what pastillation can do for capsules, and how the industry can improve clinical trials. You can also read interviews featuring Paul Donohoue from Caribou Biosciences and Luigi Naldini from the San Raffaele Telethon Institute for Gene Therapy.

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Articles featured in this issue

Business & Regulation Standards & Regulation

The Ethical Issues of Advanced Medicine

| Sumukhi Sreevatsan | 3 min read

How do we encourage the development of new cell and gene therapies without compromising our ethics?

Business & Regulation Digital Technologies

Can AI Tackle Drug Shortages?

| Jo Varshney | 4 min read

Exploring the role of AI in helping bring more medicines to market.

Manufacture Contract Manufacturing Services

May the Outsource Be With You

| Nandu Deorkar, Greg Swan | 7 min read

Experts suggest that outsourcing CGT manufacturing capabilities to CDMOs brings additional benefits, although not without challenges

Manufacture Bioprocessing - Single Use Systems

Four Thoughts: Single-Use Technologies

| Timothy Korwan | 3 min read

A quick look at trends in single use – plus top tips from Avantor for making the switch.

Manufacture Small Molecules

Capsules: Make Way for Pastillation

| Dr Subhashis Chakraborty | 4 min read

It’s already used for processing powders in many industries, but here’s why pastillation should come to pharma next.

Discovery & Development Clinical Trials

Clinical Trials: How Far We’ve Come

| Claude Price | 6 min read

Clinical trials have improved greatly over the years, but there is still much to be done.

Manufacture Advanced Medicine

Interviewing Paul Donohoue: A Guiding RNA-DNA Light for CRISPR

| Stephanie Vine | 12 min read

The story of how Caribou Biosciences developed a hybrid RNA-DNA guide to increase Cas9 specificity.

Other issues of 2024