Spray It Again, Sam
Vapor jet printing of small molecule drugs could have potential in candidate screening – or even delivery
With extensive experience in vapor jet printing small molecular organic electronic materials, a team from the University of Michigan led by Max Shtein (professor of materials science and engineering) has more recently recognized that the technology could have potential in small-molecule drugs (1). By thermally evaporating an API into a stream of inert gas and spraying the vapor onto a cool substrate, the technique can create a crystalline film of API. The research team has already tested a variety of APIs, including caffeine, paracetamol, ibuprofen, tamoxifen, BAY 11-7082 and fluorescein.
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