Spray It Again, Sam

With extensive experience in vapor jet printing small molecular organic electronic materials, a team from the University of Michigan led by Max Shtein (professor of materials science and engineering) has more recently recognized that the technology could have potential in small-molecule drugs (1). By thermally evaporating an API into a stream of inert gas and spraying the vapor onto a cool substrate, the technique can create a crystalline film of API. The research team has already tested a variety of APIs, including caffeine, paracetamol, ibuprofen, tamoxifen, BAY 11-7082 and fluorescein.