The Power List 2020 – Small Molecules
Neville Isdell Chair in African-centric Drug Discovery & Development and South Africa Research Chair in Drug Discovery
As director and founder of H3D, a research and development centre at the University of Cape Town, Chibale is dedicated to dispelling afro pessimism – including the idea that Africa has nothing to contribute to the global economy. Chibale’s research focuses on delivering treatment options for tuberculosis and malaria that are both safe and affordable while also creating jobs.
“I believe polypharmacology will go a long way to address and delay the emergence of drug resistance arising from mutations in a single target. It will also have the added advantage of benefiting patients by minimizing the pill burden and cost associated with combination drug regimens which currently require two or more small molecules that inhibit different single targets to be combined."