Discovery & Development

A “smart” synthetic patch uses live pancreatic cells to painlessly deliver insulin through microneedles – on demand

This application note explores the use of the Morphologi G3-ID for Morphologically-Directed Raman spectroscopy (MDRS) to identify and analyze contaminants including protein aggregates present in a stressed sample of lysozyme, and to compare particles held in suspension within a thin path wet cell with those collected on a filter membrane.

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Industry is beginning to appreciate how formulation microstructure makes a fundamental contribution to dermal drug delivery – and this new understanding emphasizes the key role of excipients.

Statisticians are vital in the pharma industry, but rarely do they receive public fanfare for their work. The Award for Statistical Excellence in the Pharmaceutical Industry aims to change the status quo.

A new technique allows scientists to see conformational changes caused by ligand binding in real time, opening up new screening options for drug discovery.

Pharma companies are notoriously protective of their intellectual property, so it’s a big deal to open up and give knowledge away for free. Nevertheless, it is the path that LEO Pharma took with its Open Innovation platform – and they’ve learnt that, if you give a little away, you can expect much in return.

The drug delivery field may be about to see dramatic shifts in accepted modalities. Nanoparticles, targeted delivery systems and a move from oral to transdermal routes will all play a part in tomorrow’s drug delivery landscape.

Glass is the most important primary packaging material for injectable drugs, but the demanding requirements of today’s sensitive biologicals mean that we must consider newer, safer alternatives.

Could light-activated quantum dots put the “antibiotic apocalypse” on hold?