Discovery & Development

Noven has developed around one-sixth of approved New Drug Applications for transdermal patches…

Drug delivery by inhalation promises convenience and speed in many applications from the emergency room to home-based self-administration. But to succeed, the interactions between formulation, device and metering mechanism must be perfectly balanced with human factors. These challenges are a source of fascination for those looking to deliver drugs less invasively.

New drug delivery technologies have their place, but so too do traditional needle injections…

3D printing is starting to sound attractive - but we really need to understand our powders.

Could exosome encapsulation be the secret to delivering higher potency in chemotherapy?

Could Hepatitis E breathe new life into old drugs in the fight against cancer?

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.