Cookies

Like most websites The Medicine Maker uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Discovery & Development Drug Discovery

Solutions In… the Skin-Biome

We have all heard of probiotics. These defenders of the gut environment have been shown to assist in healing wounds, preventing infection and strengthening our gut barrier. But the role of these “good” bacteria doesn’t begin and end in our bowels; microbes carry out equally important activities on the surface of skin. Catherine O’Neill, Professor of Translational Dermatology at the University of Manchester, began investigating structures in the skin that make it an efficient barrier against the body's external environment 15 years ago. Now, at the helm of SkinBioTherapeutics, O’Neill and her team are exploring the potential of probiotic bacteria in applications for skin health and disease.

Catherine O’Neill, CEO of SkinBioTherapeutics and professor of Translational Dermatology at the University of Manchester.

What is the story behind SkinBioTherapeutics? 
As an academic, I had a historic interest in the role of the gut barrier and its ability to prevent anything toxic or infectious from getting across the gut and into the bloodstream. Years of research has proven the integral role of bacteria in strengthening the barrier function in the gut and, given this link, it wasn’t a huge leap to question whether the skin microbiome might also participate in the skin’s barrier function! 

My team and I were able to identify a particular bacterium that had positive effects in skin models at my lab at the University of Manchester. SkinBioTherapeutics was then set up to develop this bacterium, Skinbiotix, as a therapeutic for skin in health and disease.

When we began we could only make a tiny amount of Skinbiotix in a test tube in my lab. We’ve now shown that we can scale it up and manufacture it with a third party and we’ve formulated it into a cream. 

Read the full article now

Log in or register to read this article in full and gain access to The Medicine Maker’s entire content archive. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Medicine Maker magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

About the Author

Maryam Mahdi

Assistant Editor

After finishing my degree, I envisioned a career in science communications. However, life took an unexpected turn and I ended up teaching abroad. Though the experience was amazing and I learned a great deal from it, I jumped at the opportunity to work for Texere. I'm excited to see where this new journey takes me!

Register to The Medicine Maker

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Medicine Maker magazine

Register