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Discovery & Development Drug Discovery

The Killer Combo

Bacteria are constantly evolving to be antibiotic resistant and are a real and present danger to our ability to treat common infections and carry out standard medical procedures, including organ transplantation, major surgery and cancer chemotherapy, among others. According to the O’Neill UK government AMR report (2016), global deaths from AMR may reach 10 million per year by 2050, which is more than cancer and diabetes combined (1).

Innovation in both the short and long term is essential if mankind is to keep pace with ever smarter and deadlier microbes. The fight to outsmart infection falls broadly into rapid diagnostics technology and targeted treatment strategies involving new and updated antibiotics.

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  1. J O'Neill, ”Tackling drug-resistant infections globally: Final report and recommendations. Review on Antimicrobial Resistance” (2016). Available at: bit.ly/2sGcZOz.
  2. WHO, “Antimicrobial resistance” (2018). Available at: bit.ly/2EdaHLq

About the Author

Anthony Coates

Professor of Medical Microbiology, St George’s, University London; Founder and Chief Scientific Officer, Helperby Therapeutics.

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