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Manufacture Small Molecules

Amine Alchemy

Researchers from The Scripps Research Institute claim to have developed a new method for synthesizing amines, which they describe as being akin to “taking dirt, and then adding a bit of rust, putting it all in a blender and ending up with gold” (1).

In fact, complex amines are often more expensive than gold because they can be challenging (or even impossible) to make using traditional methods. This includes many with particularly desirable properties for drug developers, such as resistance to breakdown by enzymes in the body.

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