Subscribe to Newsletter
Manufacture Vaccines, Clinical Trials, COVID-19

Don’t Exclude the Aged

Despite being at higher risk of severe COVID-19, older adults are in danger of being excluded from more than 50 percent of COVID-19 clinical trials and 100 percent of vaccine trials, according to a review of COVID-19 trials on (1). The authors evaluated trials based on their risk of excluding adults over 65 years old and found that most trials featured either age cutoffs or broad, unspecified exclusions.

Although they acknowledge that some exclusion will always be necessary, the authors argue that enrollment of greater numbers of older adults in clinical trials is possible with advance preparation, staff training, and aging expertise. Senior author Sharon Inouye, Director of the Aging Brain Center in the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife, believes that many of the exclusion criteria are “not well-justified, and appear to be more for expediency or convenience of the trialists.”

Receive content, products, events as well as relevant industry updates from The Medicine Maker and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

  1. BKI Helfand et al., JAMA Intern Med, [Epub ahead of print] (2020). DOI: 10.1001/jamainternmed.2020.5084
About the Author
Stephanie Vine

Making great scientific magazines isn’t just about delivering knowledge and high quality content; it’s also about packaging these in the right words to ensure that someone is truly inspired by a topic. My passion is ensuring that our authors’ expertise is presented as a seamless and enjoyable reading experience, whether in print, in digital or on social media. I’ve spent fourteen years writing and editing features for scientific and manufacturing publications, and in making this content engaging and accessible without sacrificing its scientific integrity. There is nothing better than a magazine with great content that feels great to read.

Register to The Medicine Maker

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Medicine Maker magazine