Formulation

Can supersaturation save us from solubility problems?

This article explains how an inline probe was used to monitor a granulation at three different scales to confirm that, in each case, the granules produced were the same size, and more importantly produced tablets of identical quality as quantified by hardness.

Experts come together to discuss the chemistry of solubility and the drug delivery solutions of the future for dealing with poorly soluble compounds.

Robust formulation and coating expertise are required to get the best results with continuous coating.

Can hair follicles and nanotechnology help topical drugs overcome the skin barrier?

David Banks offers a warning on using inappropriate lyophilization placebos.

Researchers say cancer should involve more frequent treatment at lower doses.

With illegal drug use rising, can a cancer drug be repurposed to cure cocaine addiction?

In this article, we take an introductory look at how TDA works, the information it provides and its complementary application to other techniques within the drug development workflow. In addition, example case study data will showcase the performance of TDA relative to dynamic light scattering (DLS) for assessment of the impact of a range of parameters on the monomer-dimer-hexamer equilibrium of insulin.

In this article, triple detection SEC and MDRS are considered within the context of characterizing complex drug formulations, with specific case studies and results illustrating their application.