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Formulation

Discovery & Development Business Practice

Resonant mass measurement as an analytical tool

Predicting and measuring protein aggregation is a critical challenge in the formulation of biopharmaceuticals. This article describes an analytical tool that hits the ‘sweet spot’ of protein aggregation measurement

Discovery & Development Business Practice

Gold therapy using dynamic light scattering

This article explains how dynamic light scattering (DLS) can be used to gather particle size distribution data for the successful use of nanosized colloidal gold in drug delivery applications.

Manufacture Facilities

Nominations for The Power List 2017

| Stephanie Vine

Nominations for the 2017 Power List are now open and will close on February 1, 2017.

Discovery & Development Small Molecules

Small But Not Forgotten

Large molecules may grab the bulk of industry headlines, but small-molecule drugs are still pulling their weight.

Discovery & Development Drug Delivery

The Soft Side of Drug Delivery

| Keith Tanner

Tablets and capsules are often the “go-to” choice in oral drug delivery, but what about innovations other areas?

Discovery & Development Drug Delivery

There Was Plenty of Room at the Bottom

| Merari Tumin Chevalier

What started as a vision of miniaturization is now beginning to have a profound influence on drug delivery.

Discovery & Development Formulation

Formulating for the Perfect Tablet Finish

| Ali Rajabi-Siabhoomi

When it comes to film coating, there’s more than meets the eye. Is the drug or tablet core sensitive to acidity or moisture? What release profile is needed? And finally, how will the patient react to the finished product?

Discovery & Development Drug Delivery

Bioavailability by Design

| Stephanie Vine

Few oral biologics have made it to market, and though the challenges are well known, the benefits are huge and the task is not impossible. New technologies can help.

Discovery & Development Business Practice

Combining spectroscopy: a new approach to meeting new pharmaceutical challenges

Automated image analysis has been combined with Raman spectroscopy to achieve component-specific size and shape analysis of active ingredients, supporting and accelerating the commercialization of both innovator and generic pharmaceutical products.

Discovery & Development Business Practice

Investigating the deagglomeration profiles of dry powder inhaler formulations

Which equipment can measure how the particle size delivered by a dry powder inhaler (DPI) changes as a function of applied air flow rate, providing a deagglomeration profile which can be used to compare the performance of different formulations in a device and improve drug delivery.

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