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Advanced Medicine

Discovery & Development Business Practice

Determining fluorescence Limit of Detection with Nanoparticle Tracking Analysis

NanoSight instruments can also operate in fluorescence mode where only fluorescently labeled particles are detected and measured. This application note works through an experiment to approximately establish a baseline in terms of the fluorescence limit of detection for a given fluorophore.

Manufacture Advanced Medicine

Brave New Factories

| Brian Hampson

Manufacturing specialists must develop cell therapy factories that can meet high demands.

Manufacture Advanced Medicine

Freeze-Dried Pharma

| James Strachan

Lyophilized gene networks synthesize biomedicines ondemand – with just a sprinkle of water.

Manufacture Standards & Regulation

Regulating a 3D-Printed Future

| Akm Khairuzzaman

Sitting Down With… Akm Khairuzzaman, a 3D printing expert from the FDA.

Manufacture Facilities

Nominations for The Power List 2017

| Stephanie Vine

Nominations for the 2017 Power List are now open and will close on February 1, 2017.

Discovery & Development Business Practice

Measurement and characterization of protein-LMW compound interactions

Measurement and characterization of binding interactions between proteins and low-molecular weight (LMW) ligands are a focus of academic research and drug discovery. Isothermal titration calorimetry directly measures heat released or absorbed in a binding event, providing means for studying protein-small molecule interactions in solution without the need for labeling or immobilization. Importantly, ITC is often utilized to characterize differences in entropic and enthalpic contributions to binding of novel ligands.

Manufacture Packaging

Glass delamination brought under control

Dr. Bernhard Hladik from SCHOTT breaks down the delamination phenomenon and describes how pharma manufacturers can effectively fight back.

Manufacture Business Practice

Catapulted to the Top

Sitting Down With... Keith Thompson, CEO of the Cell and Gene Therapy Catapult, UK.

Manufacture Advanced Medicine

Personalized Medicine × Nanotechnology

The combination of genomic profiling and high-tech targeted drug delivery is opening up a new front in the fight against cancer.

Discovery & Development Business Practice

Design and formulation of nanomedicines

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

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