DNA vaccine helps turn patients’ own cells into antibody-producing factories
Stephanie Sutton |
Vaccination against dengue virus is challenging to say the least, but researchers from the University of Pennsylvania believe that synthetic DNA could hold the answer. Specifically, they believe that DNA-encoded monoclonal antibodies could be used as an instant vaccine platform (1). Dengue fever is a mosquito-borne viral infection, but current vaccines do not provide protection against all four strains of the disease. In fact, vaccination against one strain could actually make patients more vulnerable to future infections because of the disease’s complex relationship with antibodies.
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