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Vaccines

Manufacture Business Practice

Failure to Engage

| Stephanie Vine

Could public health suffer if the pharma industry doesn’t learn to win back trust?

Manufacture Business Practice

Direct visualization, sizing and concentration measurements of drug delivery nanoparticles

In this application note, we discuss how Nanoparticle Tracking Analysis (NTA) is used to measure the size and concentration of nanoparticles used for drug delivery, such as liposomes, in order to determine efficacy and rate of uptake, degradation and clearance from the body.

Manufacture Vaccines

The Cold War

| James Strachan

Is a vaccine for the common cold impossible? Scientists believe not

Manufacture Vaccines

Fighting Flu

| Derek Gatherer

Can bioinformatics point the way towards a universal flu vaccine?

Manufacture Vaccines

A Universal Shot

| Derek Gatherer

A universal flu vaccine is not impossible for the industry – we just need bioinformatics.

Manufacture Vaccines

Plague Prevention

| Stephanie Vine

Bioterrorism concerns prompt the UK government to fund development of a vaccine for plague.

Manufacture Business Practice

When Free is Not Good Enough

| Stephanie Vine

Why has Médecins Sans Frontières rejected an offer of free vaccines from Pfizer?

Manufacture Biosimilars

The optimization and scale-up of high shear granulation

This article explains how an inline probe was used to monitor a granulation at three different scales to confirm that, in each case, the granules produced were the same size, and more importantly produced tablets of identical quality as quantified by hardness.

Discovery & Development Business Practice

Assessing Drug Encapsulation Efficiency using Nanoparticle Tracking Analysis

In this application note we describe the use of Nanoparticle Tracking Analysis (NTA) for size and concentration measurements of drug delivery nanoparticles. In addition, by using a fluorescently tagged drug molecule, it was possible to determine how many drug delivery nanoparticles had successfully been loaded with drug molecules.

Manufacture Vaccines

The Conjuror of Conjugation: Lessons Learned with Andrew Lees

Andrew Lees lightheartedly states that he has built his career on two tenets: multivalency and being lazy. And it’s worked out well; while moonlighting as a magician, he has developed the conjugation chemistry behind some of the world's most-used vaccines. Here, he explains how he learned to combine science and magic.

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