The EMA says it will review its standards for first-in-human trials

A survey-based report highlights wildly inaccurate drug demand projections

Tumor cells and phages inspire a new drug delivery method targeting the placenta

Cell therapy successes are widely hailed as breakthroughs, but will adverse effects and patient deaths hold the field back?

Automated image analysis has been combined with Raman spectroscopy to achieve component-specific size and shape analysis of active ingredients, supporting and accelerating the commercialization of both innovator and generic pharmaceutical products.

Which equipment can measure how the particle size delivered by a dry powder inhaler (DPI) changes as a function of applied air flow rate, providing a deagglomeration profile which can be used to compare the performance of different formulations in a device and improve drug delivery.

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. This article provides practical guidance on using automated imaging for efficient agglomerate detection.

High concentration, low-viscosity, stable therapeutic protein formulations are needed to enable low-volume parental administration. This article explores how a fully automated light scattering system supports the rapid screening of small volume samples in well plates for the rapid identification of suitable biologics during early phase development.

OMNISEC measures the Critical Quality Attributes of polymeric pharmaceutical excipients with unrivalled sensitivity supporting their efficient use to formulate safe and effective pharmaceutical products.

Measurement and characterization of binding interactions between proteins and low-molecular weight (LMW) ligands are a focus of academic research and drug discovery. Isothermal titration calorimetry directly measures heat released or absorbed in a binding event, providing means for studying protein-small molecule interactions in solution without the need for labeling or immobilization. Importantly, ITC is often utilized to characterize differences in entropic and enthalpic contributions to binding of novel ligands.