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Discovery & Development Drug Delivery

Chemotherapy All Wrapped Up

| William Aryitey

Could exosome encapsulation be the secret to delivering higher potency in chemotherapy?

Business & Regulation Business Practice

Fighting Falsifiers

The EU takes the fight to the falsifiers with a new plan to implement packaging safety features.

Manufacture Standards & Regulation

Competition Crackdown

The UK Competition and Markets Authority (CMA) has handed out a £37.6 million fine to GSK for paying out “value transfers totaling over 50 million pounds” to competitors between 2001 and 2004 to delay the introduction of generic versions of its branded anti-depressant drug, Seroxat (paroxetine).

Manufacture Small Molecules

Suspended Amination

Chemists solve a 46-year- old problem to develop a new drug modification method.

Discovery & Development Drug Delivery

Why We Like Virus-Like Particles

Could Hepatitis E breathe new life into old drugs in the fight against cancer?

Business & Regulation Business Practice

Heroes of Medicine Making

| Stephanie Vine

Power List: Last year many nominated business leaders, but did we miss any important unsung heroes?

Discovery & Development Business Practice

Design and formulation of nanomedicines

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

Discovery & Development Biosimilars

Taylor Dispersion Analysis explained

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.

Discovery & Development Business Practice

Accelerate liquid formulation development for protein biopharmaceuticals

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

Discovery & Development Business Practice

Reverse engineering of a pharmaceutical formulation

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

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