Analytical Science

Surface plasmon resonance has become a go-to tool for biotherapeutic characterization.

DMS could make early drug discovery cheaper, faster and more efficient.

Sitting Down With... Fiona Greer, a biosimilar guru from SGS.

What separates a good model from a bad model in bioprocess development?

We investigate the advantages and limitations of microcalorimetry in biopharma.

Health data analytics help unravel the biology behind Alzheimer’s and Schizophrenia.

The Morphologi G3-ID can be used to compare the Active Pharmaceutical Ingredients (API) within oral solid dose formualtions. Here we apply it to comparing innovator and generic versions of a product containing two APIs.

Looking at the past, present and future of counterfeit drugs screening.

Is your viscometer approaching the end of its life? Are you starting to feel that your trial and error, ‘rheology-light’ approach to formulation is becoming dated? Or are there longstanding product performance issues that you’re failing to gain traction with, where you suspect rheology may hold the answer? 

Dry powder inhalers are accepted as being complex drug products due to the interactions which occur between the active pharmaceutical ingredients (APIs) and excipients within the formulation and the way this then affects the efficiency of drug delivery by the inhaler device. Obtaining component specific particle size and particle shape distribution data can help with understanding the properties of the formulation as part of formulation or deformulation studies. This application note describes how the combination of automated image analysis with Raman spectroscopy in the Morphologi G3-ID allows the individual components present within a dry powder inhaler formulations to be independently characterized and compared.