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Discovery & Development

Discovery & Development Drug Delivery

From Brick Dust to Blockbuster?

| Sponsored by BASF

Many drug candidates are as poorly soluble as “brick dust”, making oral delivery a significant challenge.

Discovery & Development Drug Delivery

New Age Traveler

From Iceland’s volcanic springs to a lab in South Denmark; does the microbe Sulfolobus. islandicus hold the key to a drug’s safe transit through the gut?

Discovery & Development Standards & Regulation

Understanding Acceptable – Analytical Method – Submissions

| Marie Morin

Digesting regulatory guidance is not always easy, but understanding the main points – and then paying attention to the details – will improve your chances of success.

Discovery & Development Analytical Science

Data: Wanted Dead or Alive

| Ryan Sasaki

Can R&D organizations really afford to kill off analytical data that could be used for future decision-making?

Discovery & Development Business Practice

Measuring Low-Level Polymorphic Contamination using Morphologically Directed Raman Spectroscopy

| Sponsored by Malvern Panalytical

Polymorphic conversions are an ongoing problem in the pharmaceutical industry.

Discovery & Development Drug Delivery

Sparking Innovation in Drug Delivery

| Richard N. Dalby

In an industry as diverse as pharmaceuticals, there is much that different disciplines can learn from each another.

Discovery & Development

Herpes vs Cancer

| Stephanie Vine

A newly approved oncolytic immunotherapy takes on cancer using a live modified herpes virus

Discovery & Development Drug Delivery

A Soluble Solution for Drug Delivery

| Stephanie Vine

Could an ionic liquid–drug system help solve drug insolubility?

Discovery & Development Business Practice

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies

The rapid growth of the therapeutic antibody market has increased the interest in modeling of the antibody structure...

Discovery & Development Business Practice

Application of microcalorimetry in drug discovery at Exelixis

In this report, we illustrate the utility of calorimetry in making better laboratory decisions.

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May Issue of The Medicine Maker