Discovery & Development

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

Analysis of chlorhexidine drug substance using an Agilent 6545 Accurate Mass Q-TOF System and MassHunter Mass Profiler Software.

Sitting Down With... Diane Paskiet, Director of Scientific Affairs at West Pharmaceutical Services, USA.

Incremental improvements to ultra-high performance liquid chromatography (UHPLC) have failed to deliver the tangible advances that researchers really want. Sometimes, a full overhaul by re-engineering from the bottom-up is the only way to innovate and move the field forward.

Are current dosage forms really as easy and convenient for patients as pharma manufacturers say they are?

Nanoparticles help to deliver a three-in-one attack on metastatic melanoma cells

A clinical trial of an FAAH inhibitor in France goes terribly wrong, but whether the compound or manufacturing are to blame remains to be seen

Lipoprotein-nanoplatelets leave researchers hungry to explore drug delivery potential

How do we move on from a sombre start to 2016?