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Small Molecules

Manufacture Technology and Equipment

A New Angle for Marketing

| Nicolas Vertommen

Nicolas Vertommen tells the story behind HakoBio - a web-based platform for designing processes.

Manufacture Technology and Equipment

Virtual Facility Design

| Ian Sellick

Virtual reality can let you walk around facilities before they have been built.

Manufacture Technology and Equipment

Harnessing Augmented Reality

| Angelo Stracquatanio

How Google Glass inspired hands-free access to information for process engineers.

Discovery & Development Dosage Forms

Swallowability by Design

| Thomas Hein

Tablets are the most common dosage form, but have you considered all of your options?

Manufacture Small Molecules

Save Our Insoluble Compounds!

| Kohsaku Kawakami

Can supersaturation save us from solubility problems?

Manufacture Business Practice

And the Facility of the Year is…

| Stephanie Vine

Genentech’s Cell Culture Biologics Drug Substance Plant 2 in Vacaville, California.

Manufacture Advanced Medicine

Freeze-Dried Pharma

| James Strachan

Lyophilized gene networks synthesize biomedicines ondemand – with just a sprinkle of water.

Manufacture Biosimilars

The optimization and scale-up of high shear granulation

This article explains how an inline probe was used to monitor a granulation at three different scales to confirm that, in each case, the granules produced were the same size, and more importantly produced tablets of identical quality as quantified by hardness.

Discovery & Development Formulation

The Placebo Effect

| David Banks

David Banks offers a warning on using inappropriate lyophilization placebos.

Discovery & Development Business Practice

Using Taylor Dispersion Analysis to determine oligomeric state of insulin

In this article, we take an introductory look at how TDA works, the information it provides and its complementary application to other techniques within the drug development workflow. In addition, example case study data will showcase the performance of TDA relative to dynamic light scattering (DLS) for assessment of the impact of a range of parameters on the monomer-dimer-hexamer equilibrium of insulin.

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