Small Molecules

Martin Van Trieste tells the emotional story behind the creation of Rx-360

For modern medicines, I believe that liquid-filled encapsulation has the edge.

Pharma is urged to tackle the problem of polluted waste water from manufacturing plants.

What separates a good model from a bad model in bioprocess development?

What was hot in 2016? And what should pharma's priorities lie in 2017?

In this application note, we discuss how Nanoparticle Tracking Analysis (NTA) is used to measure the size and concentration of nanoparticles used for drug delivery, such as liposomes, in order to determine efficacy and rate of uptake, degradation and clearance from the body.

The Morphologi G3-ID can be used to compare the Active Pharmaceutical Ingredients (API) within oral solid dose formualtions. Here we apply it to comparing innovator and generic versions of a product containing two APIs.

What do ISPE’s 2016 Facility of the Year Awards tell us about the future direction of the industry?

How pungent camel urine could lead to new treatments for African sleeping sickness.

Dry powder inhalers are accepted as being complex drug products due to the interactions which occur between the active pharmaceutical ingredients (APIs) and excipients within the formulation and the way this then affects the efficiency of drug delivery by the inhaler device. Obtaining component specific particle size and particle shape distribution data can help with understanding the properties of the formulation as part of formulation or deformulation studies. This application note describes how the combination of automated image analysis with Raman spectroscopy in the Morphologi G3-ID allows the individual components present within a dry powder inhaler formulations to be independently characterized and compared.