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Small Molecules

Discovery & Development Business Practice

Adopting an Orphan (Drug)

| Pan Pantziarka and Gauthier Bouche

New cancer treatments may be lying right under our noses – if we are willing to take a commercial risk.

Manufacture Formulation

Beyond the Rule of Five

| Simon Pearce

We need to explore the chemical space outside of Lipinski’s rules.

Manufacture Clinical Trials

Forgotten, but not Gone

| James Strachan

A half-century-old “bet hedging” hypothesis explains the effectiveness of many drug combinations.

Manufacture Small Molecules

Beating the Resistance

Should we target minor rather than major infections with new therapeutics to best fight antibiotic resistance?

Manufacture Small Molecules

Battling the Bugs

| Stephanie Sutton

London’s Science Museum highlights superbugs and the stars that fight against them in a new exhibition.

Discovery & Development Formulation

Taste Maker

| James Strachan

Some patients, particularly children, find medicines unpalatable – and genetics could be the cause.

Manufacture Business Practice

Hopes and Fears

| Stephanie Sutton

The year 2018 will be one of yet more drug approvals, but which areas will be neglected?

Manufacture Technology and Equipment

The Transformation to Excellence-MS

| Sponsored by Millipore Sigma

How a customer focused mission to boost single-use assembly product quality and supply security led to the Mobius® MyWay Program and a manufacturing site transformation.

Manufacture Bioprocessing - Upstream & Downstream

The Problem with Poloxamers-MS

| Sponsored by Millipore Sigma

Poloxamer 188 has become an essential component of cell culture media, but lot-to-lot variability has been a problem for many biopharma manufacturers.

Manufacture Small Molecules

The Best Defense Is Good Science

| Kevin Kayser

Learn the story behind Centinel: the first Minute Virus of Mice-resistant CHO cell line.

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