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Manufacture Small Molecules

Save Our Insoluble Compounds!

| Kohsaku Kawakami

Can supersaturation save us from solubility problems?

Manufacture Vaccines

Plague Prevention

| Stephanie Vine

Bioterrorism concerns prompt the UK government to fund development of a vaccine for plague.

Manufacture Business Practice

And the Facility of the Year is…

| Stephanie Vine

Genentech’s Cell Culture Biologics Drug Substance Plant 2 in Vacaville, California.

Business & Regulation Standards & Regulation

The Fight for Transparency

| James Strachan

The EMA says “yes” to transparency, but some pharma companies have other ideas.

Business & Regulation Packaging

Serialization Standardization

| Stephanie Vine

A consortium of vendors and pharma companies search for a single, serialization standard.

Business & Regulation Biosimilars

Negotiating GDUFA II

| James Strachan

Are reduced GDUFA fees on the horizon for contract manufacturers?

Manufacture Advanced Medicine

Freeze-Dried Pharma

| James Strachan

Lyophilized gene networks synthesize biomedicines ondemand – with just a sprinkle of water.

Manufacture Business Practice

When Free is Not Good Enough

| Stephanie Vine

Why has Médecins Sans Frontières rejected an offer of free vaccines from Pfizer?

Manufacture Biosimilars

The optimization and scale-up of high shear granulation

This article explains how an inline probe was used to monitor a granulation at three different scales to confirm that, in each case, the granules produced were the same size, and more importantly produced tablets of identical quality as quantified by hardness.

Discovery & Development Technology and Equipment

The Science of Insolubility

Experts come together to discuss the chemistry of solubility and the drug delivery solutions of the future for dealing with poorly soluble compounds.

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