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White Papers

Results 71–80 of 92

Theory and Practice of Isothermal Titration Calorimetry

| Contributed by Malvern Panalytical

Dr. Adrian Velazquez-Campoy and Dr. Natalia Markova

Increase Monoclonal Antibody Purity with TOYOPEARL® Sulfate-650F C-IEX Resin for Capture and Removal of mAb Aggregates

| Contributed by Tosoh

TOYOPEARL Sulfate-650F cation exchange resin can be used for the removal of aggregates, host cell proteins and leached protein A in a single post Protein A mAb polishing step.

A buyer's guide to protein stability measurement platforms

| Contributed by Malvern Panalytical

Protein stability analysis technologies for the biopharmaceutical industry

Laser diffraction and automated imaging: complementary techniques for nasal spray development

| Contributed by Malvern Panalytical

Together the techniques of laser diffraction and automated particle imaging support the fast, cost-effective development of nasal spray products, simultaneously providing the data required for regulatory compliance; this article examines their application.

Characterization of biopharmaceutical stability with Differential Scanning Calorimetry

| Contributed by Malvern Panalytical

The intention of this whitepaper is to explain how DSC is used to characterize the thermal stability of protein biopharmaceuticals (primarily antibodies) during the selection of drug candidates to advance into development.

Measurements of protein electrophoretic mobility using DLS

| Contributed by Malvern Panalytical

This application note describes the measurement of protein mobility using the ZSP. Using the diffusion barrier method and appropriate measurement protocols, the most accurate readings possible are obtained.

Particle characterization of the active components in a pharmaceutical topical formulation

| Contributed by Malvern Panalytical

This application note describes how the combination of automated image analysis with Raman spectroscopy can deliver component specific particle characterization data for pharmaceutical blends such as topical formulations.

Most powerful tool for the detection of counterfeit drugs

| Contributed by Malvern Panalytical

Introducing Morphologically-Directed Raman Spectroscopy

How to improve performance of the Protein A capturing step

| Contributed by Tosoh

Protein A has become a well-established platform for capturing of monoclonal antibodies and Fc-fusion proteins.

Developments in Peptide Mapping Technology for the Biopharmaceutical Industry

| Contributed by ThermoFisher Scientific

Peptide mapping is a critical workflow in biotherapeutic protein characterization and is essential for elucidating the primary amino acid structure of proteins.

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