Discovery & Development

In Part Four, we address frequently asked questions related to the application of DLS to the characterization of protein therapeutic formulations.

In Part Three, we cover the basic types of DLS deconvolution algorithms used to extract the intensity weighted particle size distribution from the measured correlogram.

In Part Two, we cover the influence of concentration effects and particle interactions on DLS results and provide a roadmap for identifying and distinguishing each type of concentration effect.

In Part One, we provide an overview of the key principles of DLS: theory, correlation statistics, deconvolution algorithms, and the intensity to mass transform.

Use of a novel combination of dynamic light scattering and Raman spectroscopy to elucidate the conformational stability and structure of proteins in biopharmaceutical formulations

Javier Morales tells us why he is investigating inkjet printing for the development of buccal films for the delivery of biologic drugs.

There are many hurdles in drug development, but your chances of success increase significantly if you pay more attention to API optimization from the outset.

Clinical development is outmoded; we are witnessing serious attrition in cancer R&D. Perhaps it’s time to live and die by the mantra: “no biomarker, no trial”.

Researchers redesign existing drugs to be more biodegradable and environmentally friendly.

A digital pill submitted for regulatory approval tells caregivers if you’ve taken your medicine