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Welcome to the December issue. Upfront explores Brexit and the UK’s current Withdrawal Agreement woes, transdermal patches for drug delivery, and the exploitation of CRISPR technology to modify embryonic genomes. Giovanni Appendino explains why we should tap into the medical potential of cannabis in “In My View,” while our cover feature highlights the most innovative technologies of the past year with our Innovation Awards. And Gavin Yamey discusses how a new financial modelling tool can help bridge the funding gap for neglected diseases in “Business.” In our latest Sitting Down With… Stanley Crooke, CEO at Ionis Pharmaceuticals argues that weathering the storm when creating new platforms can lead to positive outcomes.

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Articles featured in this issue

Discovery & Development Drug Discovery

Here's to Good Science for 2019

01/15/2019 | James Strachan

Successes in the cell and gene therapy field show us that great advances can be made – without taking unnecessary risks.

Business & Regulation Trends & Forecasts

Withdrawal Symptoms

01/08/2019 | James Strachan

Brexit: As UK politicians debate the merits of the Prime Minister’s Withdrawal Agreement, we debate its potential impact for pharma...

Business & Regulation Clinical Trials

Crossing the Rubicon

01/08/2019 | Maryam Mahdi

What does the controversial genome editing work of Jiankui He mean for biomedical research?

Discovery & Development Drug Delivery

Skin Deep Problems

01/15/2019 | Maryam Mahdi

A flexible, synthetic patch helps eliminate the toxicity and invasiveness associated with long-term drug delivery

Discovery & Development Drug Discovery

Holding Back the Years

01/21/2019 | Maryam Mahdi

How are scientists seeking inspiration from plants in the fight against Alzheimer’s disease?

Business & Regulation Standards & Regulation

Business-in-Brief

01/08/2019 | Maryam Mahdi

Oscars of science, drug shortage reporting requirements, and a new gene therapy... What’s new for pharma in business?

Discovery & Development Vaccines

Spiraling Towards an Answer

01/15/2019 | Maryam Mahdi

Researchers capture the interactions of antibodies with the parasite responsible for malaria for the first time

Manufacture Technology and Equipment

Medicines Anywhere, Anytime

01/21/2019 | Govind Rao

Why use a huge manufacturing facility when biological medicines can be made in a suitcase?

Manufacture Technology and Equipment

Strokes of Genius: The Innovation Awards 2018

01/02/2019 | Stephanie Vine

The 2018 Innovation Awards are here! From capsules, to software, to high-tech mass spectrometers; we celebrate the advances of the field.

Manufacture Quality & Compliance

Staying Flexible

01/16/2019 | Firman Ghouze, Uriel Kusiatin

Rather than fearing the unknown, the concept of optionality can help you better manage it.

Business & Regulation Trends & Forecasts

Always the Bridesmaid...

01/15/2019 | Gavin Yamey

The pharma industry understands the importance of neglected diseases, but the field is still not receiving the attention it deserves.

Business & Regulation Business Practice

Staying the Course

01/18/2019 | James Strachan

Sitting Down With… Stanley Crooke, Chairman of the Board & Chief Executive Officer at Ionis Pharmaceuticals.

Other issues of 2018