Bioprocessing - Upstream & Downstream

When an industry grows rapidly, innovative approaches are required to ensure sustainable growth. Here, we speak to leaders at Ireland’s National Institute for Bioprocess Research and Training – NIBRT – to find out how a focus on talent, training and technology is changing the face of the field.

Manufacturers have gotten to grips with the complexities of batch-based bioprocesses, but breaking into the realm of continuous bioprocessing can lead to even greater efficiency.

Viscosizer TD provides automated relative viscosity measurements with high reproducibility at low viscosity, to help identify molecules with abnormally high viscosity-concentration profiles at low sample concentrations as early as possible in the development pipeline

Traditional pharma manufacturers are already dipping their toes in the waters of continuous processing, but what about when it comes to biopharmaceuticals?

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Can sophisticated (spectroscopic) sensors streamline bioprocess monitoring to better meet FDA standards?

Can sophisticated (spectroscopic) sensors streamline bioprocess monitoring to better meet FDA standards?

Cell culture media developers used to focus on maximizing protein yield. But yields are yesterday’s problem...

The challenges of battling bottlenecks in downstream processing. Sometimes a fresh pair of eyes can find new and surprising solutions.

Should product innovation or process innovation come first in biopharmaceuticals?