Facilities

The technology behind cleanrooms is well over 50 years old. Is it time for a makeover?

We should look to Warning Letters – and the subsequent solutions – to benefit from the blunders of others.

A choice of fumigants are available for fumigating microbiological safety cabinets and high-level containment rooms. One substance that is still used in the industry is formaldehyde, but given that formaldehyde is toxic, carcinogenic and corrosive, you’d be better looking for alternatives.

Microbiological approaches are faster and more advanced than ever before – so why on earth isn’t the pharma industry using them?

How did the NIH get it so wrong – and how can it move on?

In this paper, the authors describe the use of laser diffraction to analyse dry powder behaviour.

The technology has barely changed over the last 30 years – surely, it’s time for some long overdue innovation.

Nasal spray products are increasingly valued for delivering systemic as well as locally-acting therapies, most notably hormone and migraine treatments

It is clear that terminal sterilization is the gold standard for sterile drug manufacture, so why are companies so reluctant to pursue it?

Is there a ‘safe’ hold time for sterilized items? And, if so, how can those hold times be reliably validated?