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Small Molecules

Manufacture Small Molecules

Precision Medicine; Imprecise Manufacturing and Supply

Precision medicine holds much promise; are companies up to the challenge?
Manufacture Business Practice

Using Differential Scanning Calorimetry (DSC) to optimize antibody manufacturing

| Sponsored by Malvern Panalytical

In this white paper, we report the use of the thermal stability data obtained from DSC to screen conditions for viral inactivation of an antibody1.

Manufacture Business Practice

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

| Sponsored by Malvern Panalytical

See how thermodynamics can be used to improve your lead optimization process.
Manufacture Business Practice

Targeting protein/protein interactions in drug design

Protein interactions define a large fraction of the validated targets for drug development including cancer, diabetes, infection and autoimmune diseases.
Manufacture Standards & Regulation

A New Era of E&L Analysis

| Sponsored by Thermo Fisher Scientific

New technologies for extractables and leachables testing of small molecules and biopharmaceuticals.
Manufacture Business Practice

Nobel Prize for Noble Causes

| Stephanie Vine

The 2015 Nobel Prize in Physiology or Medicine praises advances in parasitic tropical diseases.
Manufacture Drug Delivery

Drugs in Disguise

How to dress drugs to help them survive in the bloodstream.
Manufacture Technology and Equipment

Realizing 3D Potential by Printing a Clearer Picture

Ronan Daly describes his research in combining inkjet printing and medicines.

Business & Regulation Small Molecules

An Instinct for Innovation

| Stephanie Vine

Sitting Down With... John Talley, Chief Scientific Officer at Euclises Pharmaceuticals, St. Louis, USA.
Manufacture Business Practice

Characterization of IgG monomers & their aggregates

| Sponsored by Malvern Panalytical

Two antibody samples were characterized using column calibration and multi-detection SEC, and the results compared...
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February Issue of The Medicine Maker