Small Molecules

The first switch from batch to continuous manufacturing has been made – and approved by the FDA. Will pharma’s future be continuous?

Functionalized glass is shown to trigger nucleation of specific crystal forms

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Work performed in conjunction with Spiber Technologies, Uppsala, Sweden. Use of dynamic and electrophoretic light scattering to assess the effects of protein formulation composition

A choice of fumigants are available for fumigating microbiological safety cabinets and high-level containment rooms. One substance that is still used in the industry is formaldehyde, but given that formaldehyde is toxic, carcinogenic and corrosive, you’d be better looking for alternatives.

“Batch is best,” according to many in the industry, but when cost reductions and greater efficiencies are a priority, continuous processing is becoming increasingly compelling.

Regulators come down hard on facilities that come up short.

Chemists solve a 46-year- old problem to develop a new drug modification method.

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.