Small Molecules

In this application note we describe the use of Nanoparticle Tracking Analysis (NTA) for size and concentration measurements of drug delivery nanoparticles. In addition, by using a fluorescently tagged drug molecule, it was possible to determine how many drug delivery nanoparticles had successfully been loaded with drug molecules.

Viscosizer TD provides automated relative viscosity measurements with high reproducibility at low viscosity, to help identify molecules with abnormally high viscosity-concentration profiles at low sample concentrations as early as possible in the development pipeline

Andrew Lees lightheartedly states that he has built his career on two tenets: multivalency and being lazy. And it’s worked out well; while moonlighting as a magician, he has developed the conjugation chemistry behind some of the world's most-used vaccines. Here, he explains how he learned to combine science and magic.

Traditional pharma manufacturers are already dipping their toes in the waters of continuous processing, but what about when it comes to biopharmaceuticals?

Our experience with implementing serialization, has shown us that anti-counterfeiting is just one of its potential uses.

Antibody drug conjugates offer a great deal of potential for drug targeting, but what’s the best way of linking drugs and antibodies?

Where did Quality by Design come from? Where will it lead to in pharma? And is there a day when the concept will no longer exist?

Can the stress of space force fungi to produce novel therapeutics?

Sitting Down With... Ann Hayes, Owner, The Ann Hayes Consultancy, Stevenage, UK.

Hot Melt Extrusion helps to enable pharmaceutical companies to literally solve their solubilization issue.