Small Molecules

In this white paper the specific mechanisms by which nanoparticles are designed and formulated for therapeutic purposes and in which NTA has had a significant part to play is discussed.

Taylor Dispersion Analysis is an ultra-low volume, microcapillary flow technique for sizing and stability of biomolecules in complex solutions, and offers advantages for orthogonal and complementary biophysical characterization measurements.

The work presented here illustrates how Differential Scanning Calorimetry (DSC) is used in the early stages of protein characterization to rapidly provide critical data about protein stability that can be used as a guide to support and accelerate liquid formulation.

The Morphologi G3-ID can be used to generate component-specific particle size and shape data required to aid the reverse engineering of solid oral dose formulations. Here, we provide an example case study for a powder formulation.

Does the fabrication of nanoparticles and nanocapules sound complex? Don’t worry – layer by layer technology allows for simple fabrication of complicated stuff.

Precision medicine holds much promise; are companies up to the challenge?

In this white paper, we report the use of the thermal stability data obtained from DSC to screen conditions for viral inactivation of an antibody1.

See how thermodynamics can be used to improve your lead optimization process.

Protein interactions define a large fraction of the validated targets for drug development including cancer, diabetes, infection and autoimmune diseases.

New technologies for extractables and leachables testing of small molecules and biopharmaceuticals.